There is a wealth of information about Prolia on the Facebook Self-help group Prolia (Denosumab) side effects/effets secondaries support group. They have an entire library of studies and articles dedicated to helping people be more aware prior to taking this medicine.

Wonder what the other drugs were that they told her.

I think what the doctors were trying to convey is once I start on any of four specific medications, I need to stay on "an osteoporosis medication" indefinitely (not necessarily the SAME medication). The endocrinologists were suggesting Reclast since that can supposedly be stopped without having to take another medication. But, at my last appointment the endo suggested starting with Evenity, then Reclast after. I am researching options and looking for "reasons" for each to see if they fit my situation. It seems most doctors "always use" a specific medication without considering if the issue is with osteoclast or osteoblast activity. If I agree to a medication, I would need to know the specific medication is what "I" need based on my health and test results since the wrong medication for a patient can actually have a negative impact. When the doctor just prescribes "the usual" without more in depth testing or conversation, I am cautious ..., and that leads me to research for myself. I am hoping insights from this group will be helpful.