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SBRT for lung cancer: What's your experience?

Lung Cancer | Last Active: May 3 11:07am | Replies (39)
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@tumanic

I had SBRT treatment twice. First was for two tumors (one in each lung) and two years later for a tumor in my right lung. Both times I had pneumonitis 90 days after treatment. Breathing was very difficult with exertion, I wound up sleeping upright to breathe. Prednisone fixed the problem after months on the drug but caused diabetes that had to be managed. Also had adverse affects on my heart. I’m curious why you cannot have immunotherapy now, what caused that? I have a new tumor emerging and was hoping immunotherapy might be an option.

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vic83 | @vic83 | Dec 27, 2023

Sorry for delay in responding. My browsers needed to be reset to access this site.
My CT scans have also indicated the presence of Interstitial Lung Disease (there are many types!) as well as my multifocal lung cancer. After my Pulmonologist indicated "radiation induced pneumonitis" and told me I could not do immunotherapy, I did some research and found the following articles that explains some things:
"Management of Lung Cancer in the Patient with Interstitial Lung Disease"
https://academic.oup.com/oncolo/article/28/1/12/6847063
Here is another article (more technical)
"Radiation recall pneumonitis induced by PD-1/PD-L1 blockades: mechanisms and therapeutic implications."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499987/

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