I have been on 20 mcg or a quarter of a dose of a Tymlos sample for a couple months. I tried the whole dose last Spring and had horrible side effects. I asked my endo about half a dose and he was fine with that. Later, he said that the way it works by kicking in parathyroid hormone briefly, it may not matter how much I take. I just had my DEXA scan and the results are remarkable. Lower back T-score -2.3, previously -2.9, 8.5% improvement. Left hip T-score -1.7, previously -2.3 11, 6% improvement. Right hip T-score -2.2, previously -2.5, 6.1% improvement. I have been taking Strontium which may have altered the results. I also take red algae calcium, vitamin K2 MK7, Boron, Magnesium, vitamin D3 and Collagen peptides.
I have broken 4 bones in the last year and a half. I asked my endo and his nurse to request insurance prior authorization for Tymlos several times in the last 2 months. I found out yesterday that they never did. Now I'm afraid I will never get insurance approval for Tymlos with my good DEXA results. It is difficult to tell what helped my scores, the Tymlos or the Strontium or both. I am waiting for the results from my CTX and P1NP blood tests.
I am very sensitive to medications and have low blood pressure. I take the Tymlos at night. At first, the dizziness, headache and imbalance lasted all day. Now, I rarely notice it during the day, but of course I'm only on a quarter of a dose. I very much appreciate this website, where I learned that I am not the only one taking less than full dose.
You might ask your endo to use the prior dxa with the insurance. After their oversight or neglect. If your insurance won't approve you may be eligible for pharmaceutical company help. Usually all they require is a prescription. Will your endo still prescribe now that your numbers have improved. Your results are so good that I don't think it can be the strontium alone. I would maintain the quarter dose. It is interesting that your endo suspects it might not matter how much you take. If the 80 mcg only yields 36mcg bioavailability, maybe the other 44mcg only causes side effects. Best wishes. https://www.tymlos.com/hcp/resources/#:~:text=What%20to%20do%20if%20TYMLOS,who%20cannot%20afford%20their%20medication.