I started taking it at night, but switched to mornings. I was waking up with a headache. In the first months I would rest after the shot and even took my blood pressure before and after. But after awhile I found that side effects (which for me lasted maybe 2 hours) eased if I got up and out. I actually found it more tolerable by being active! Everyone is different and you can play around with it.

I ramped up the dose and mostly took 6-7 clicks worth versus the full 8 as I have written before. I had excellent gains. I would actually vary the dose depending on what I had to do that day: 6 clicks for a day with something important or onerous, and 7 the rest of the time. At the very end I did manage a full dose!

Tymlos was the ONLY med I could tolerate and I am so grateful. I am going to try Evenity a few times and then my doc will do a 20% Reclast test dose which I may stick with, due to my sensitivities. Good luck!