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CAR-T cell Therapy: Joint and muscle pain

CAR-T Cell Therapy | Last Active: Dec 20, 2023 | Replies (37)

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@esperanza3a

My oncologist says the weakness and joint pain comes with low platelet and red blood cell counts - the result of the CarT cells still active after infusion mid August. I should feel better with time and I do have many good days.

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Replies to "My oncologist says the weakness and joint pain comes with low platelet and red blood cell..."

Interesting that your oncologist is relating the weakness and joint pain to low platelet and red blood counts. My wife really didn't experience either, mostly really low WBC and neutrophil levels. All three independent oncologists, only one who is a CAR-T center practitioner, have downplayed any role that CAR-T has had. But yet, all of her aches and pains and apparent 'tears' showed up post treatment. We keep thinking it is inflammatory in nature but mush more long term than is apparent with CRS related inflammatory responses. Some findings suggest it might be a side effect from having been on Cipro for a period of time post CAR-T, probably longer than might be typical but was due to her low immunity and not yet being able to be put on something else for the first few weeks after being discharged on day +11.