Hi I’m getting my first pluvicto treatment tomorrow can you give me any advice or how the side effects were and how long you had to stay away from people 2-3/days thank you Dave

I think insurance companies prefer Docetaxel versus Jevtana when Castrate Sensitive. At least that is what I have been told. Jevtana also seems to have fewer side effects and is better tolerated. My understanding is that for some who become Castrate Resistant doctors may choose a combination of Jevtana and Carboplatin. My understanding regarding Pluvicto is that people respond in three ways. 1) It does not work. 2) It works but only drops PSA 50%, or 3) there is a profound response to the treatment. I do not know why Pluvicto works for some and not others. I have the same questions about chemotherapy and ADT. I'm guessing it depends on the type of PC mutation that one is experiencing. Is there BRAC1 or BRAC2 involvement or some other mutation that one might not be aware they have. Prostate Cancer sucks. We have to keep fighting.

I can say for me personally, I was one of the very few that it didn't work. I would say do the Pluvicto and might work wonders for you. The side effects from Pluvicto were non existent for me. I just had some fatigue. I drove myself 50 miles to get it and drove myself back home. I slept in another room away from wife for 3 days as a precaution. As I said before, it just was doubing my PSA and we stopped it. Just monitor it. I gave it 3 rounds until I pulled the plug. The difference between Jevtana and taxotere chemo for me is that I found Jevtana to be milder and I didn't lose my hair. Jevtana targets prostate cancer cells better and leaves the good ones alone. Like I said everyone is different and what might work for me might not work for you and visa versa. I have not changed my lifestyle and continue to eat the foods I want but in smaller portions.

Since it's been 10 years, Taxotere was the 1st option and I believe Jevtana didn't get approved until a little later. Jevtana targets the prostate cancer cells and doesn't bother the good cells as much compared to taxotere. When it came to Pluvicto, I was in the minority. Most guys get good results unfortunately it made my PSA rise after 3 infusions. I went from around 2.56 to 20.83 after 3 infusions.