From my understanding some basal cell lesions can become itchy or painful as they begin and/progress because of the changes in the skin surrounding them. During a discussion with my dermatologist, she explained that because it’s an abnormality in skin, our immune system reacts to the site, sending specialized blood cells, eosinophils, which can cause itching because of the histamine reaction. Mine was itchy… Did you have the subcutaneous tumor removed? Has the pain gotten any better?