I totally agree about infections due to biologics. I was on Actemra for a year and referred to it as a miracle drug. It put my Polymyalgia Rheumatica into remission. Then I developed influenza A (even though vaccinated), pneumonia, sepsis and Afib. Nearly died. Then back to the hospital for 19 days with pleural effusion, a collapsed lung and mysterious infections leading again to Afib, severe anemia and liver damage due to antibiotics.
Needless to say I am off the biologic and feeling good. However the sepsis caused damage to many organ systems.
Recently my rheumatologist wanted me to go back on a biologic. I said no. I will deal with the arthritis in my hands. At least it won’t kill me.
My belief is that doctors seem to be pushing biologics for every malady. It makes sense to suppress autoimmune diseases, but to suppress our immune systems leads to potentially fatal infections. No more for me!