@frank, @anniebrook Just a suggestion for you..... keep your pippets in the refrigerator. Then the application won't "sting like a buggar". The newest dry eye treatment is Xiidra. After several years of deteriorating cells even with Restasis, my ophthalmologist had me try Xiidra. Within a few months my eyes, according to him, "looked the best I have seen them in 3 years". I am thrilled. We need every cell we can muster to be able to have good eyesight. I am just adding info, not making a recommendation. I also use the doubling up method to save $$$$. That works well for me. I add a preservative-free gel during the day and a nighttime ointment when I go to bed. My only other option was to go live in a rain forest.........where the humidity is above 80%. Be safe, be well, protect your eyes.