Thank you. I took Methotrexate with Humira at the beginning, then dropped Methotrexate and only took Humira. From that point (almost 5 years) all was fine and Humira worked very well for me. At the 5 year marked, it seemed to be working too well, for whatever reason started lowering my immune system more than before…which contributed to the 3 episodes of pneumonia. No other known reason. I’ve learned that for me, any type of stress (good or bad stress) is likely to cause a flare of Uveitis or joint flare. It often happened when traveling due to the stress of airports, flying etc…and during “good” stress, once as we waited in the hospital for our daughter to give birth for the first time. During our wait, suddenly my foot became swollen & red, and painful. So, I do what I can to keep calm in stressful situations….not always successfully! I have not had a Uveitis flare in 2 years , when typically I would have an episode a couple times each year, no matter how minor and quickly treated. I still have minor joint flares which will come and go quickly. It’s a “wait & see” process to see what I will do in the future as far as biologics treatment…