@maryann1753 . Good afternoon. I have had a knee replacement also. It was well done and I recovered quickly. According to my neurologist, the fascia around the knee became restrictive. All of a sudden it became cranky and painful after my morning walk. At this point, I have two questions. 1. Have you experienced or heard of MFR, Myofascial Pain Release therapy. It is a way of releasing the restrictions around the knee. 2. Are you now or have you tried using a mixed dosage of medical cannabis that includes CBD, for example, 2:1 or 2 parts CBD to 1 part THC. CBD appears to have the ability to reduce inflammation in concert with the THC. I now use a 2:1 CBD/THC dose in the morning and a 1:1 CBD/THC in the afternoon. I also use a topical of 3:1 CBD/THC at bedtime. Here is a link that discusses dosage amounts for different desired results https://cannabis.net/blog/medical/what-are-cbdthc-ratios-and-their-benefits Hope this info is helpful. Be safe and hopefully have a pain free day.