@apopson
Welcome to Mayo Clinic Connect!
Very worrisome to hear about your repeat infections. Are the infections caused by the same bacteria?
I don’t have any experience myself with biologics but I’m sure there are many members here that do.
Since biologics treatment affects your immune response to your autoimmune disease it would also make you susceptible to infections.
I have been treated with immunosuppressants - Imuran-for several months but stopped it because of many bacterial infections.
May I ask what disease you are being treated for?