This discussion has me reviewing my thoughts on B6. A half year ago, my neurologist invited me to try EB-N5, a medicinal food containing the water-soluble form of B6, pyridoxal phosphate, which he assured me (and it has since been confirmed by other doctors) is a form of B6 that does not lead to toxicity––unlike pyridoxine hydrochloride, another form of B6, found in food and supplements, that can lead to toxicity. Thus far, I've been taking EB-N5 with no discernable ill effects. What has me wondering, however, is the B6 I've been getting for years from the usual supplements many of our doctors recommend: B1, B6, B6-Complex, B12, and a multivitamin. I'm wondering if the taking of those B6s for several years now have contributed to the high level of B6 that my recent labs have shown. I would like to continue with the EB-N5 (pyridoxal-5-phosphate), but perhaps cut out the supplements containing B6 (pyridoxine hydrochloride). I have more labs next week, followed by a meeting with my neurologist. I'll discuss this with her. –Ray (@ray666)