I’m over 4 years on Anastrazole and have had no issues with it. I was post-menopausal however. I had ER+ PR+ breast cancer with lymph node involvement. My range of risk of recurrence is 17-38%. I look at it this way…use of an AI keeps me at the lower end of risk. Losing weight keeps me at the lower end of risk. Healthy eating ( upping protein, lowering carbs) keeps me at the lower end of risk. Hopefully you can take advantage of every possible thing that can lower your risk of recurrence. That way if one piece is truly impossible for you there will still be other actions in place to help reduce your risk of recurrence and keep you well. JMHO