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@diamonds

National Library of Medicine Study 3 months vs 6 months of adjuvant chemotherapy for patients with high risk stage 2 and 3 colorectal cancer: 3 year follow-up of the SCOT non-inferiority RCT

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Replies to "National Library of Medicine Study 3 months vs 6 months of adjuvant chemotherapy for patients with..."

OK, had to search for it. Skimmed the conclusions, didn't read the whole thing. Way beyond my abilities to interpret.

From the conclusions: "The findings of this research indicate that 3 months of adjuvant chemotherapy may be sufficient for some patients." That "may" is significant. Then they clarify with "For patients with low-risk stage III disease (T1–3, N1) receiving adjuvant oxaliplatin and capecitabine chemotherapy, 3 months of treatment is sufficient."

This I think is one to discuss with your oncologist. My one point of note based on my experience and that of others' experiences I've read, getting through 3 months of oxaliplatin is often not possible due to the severe side effects. A lot of patients including myself have to drop the "OX" from the FOLFOX regimen. In my case, I had cardiac problems early.

I suppose if you're in that T1-3, N1 classification, one could try the 3-month regimen studied in the paper and if not tolerated, fall back to the more standard 6 month FOLFOX6, but again, that's up to your oncologist and you.