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Multiparametric MRI (mpMRI) over diagnosis?

Prostate Cancer | Last Active: Dec 14, 2023 | Replies (32)
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@gently

handera,
two things can enhance your decision. First is the PSMA you might ask for the latest contrast Pylarify said to be better than gallium ga68. The very important second is somatic testing of the tumor (genetic testing of the tumor itself). Both will give clues about the aggressiveness of your cancer and about whether your cancer is likely to metastasize.
Prostate cancer treatment is making some interesting advancements. Pubmed the NIH and videos from your cancer treatment center (if you check the dates of publication) will give you more current information than books.
Best wishes

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Replies to "handera, two things can enhance your decision. First is the PSMA you might ask for the..."
handera | @handera | Dec 9, 2023

Thanks for this useful information, I will certainly follow up.

It seems technology is moving so quickly in all fields of science, that books can seem like “yesterday’s news”.

IMHO, well documented, published books are helpful from the POV that a fuller analysis, having reasoned and well thought out arguments, can be made with the knowledge available at the time of writing…even in scientific fields.

Sometimes new findings need confirmation and can end up being refuted.

Regarding PMSA PET-CT for prostate cancer, my doctor indicated he does not recommend that scan for someone diagnosed with my stage of PCa.

For what it’s worth PMSA PET-CT apparently exposes one to 8.4 mSv of radiation; which is significantly less than standard PET scans.
https://www.esmo.org/oncology-news/psma-pet-ct-is-a-suitable-replacement-for-conventional-imaging-in-high-risk-localised-prostate-cancer
For comparison purposes, a chest x-ray is 0.02 mSv and a transatlantic flight is 0.1 mSv.

Of course, from what I’ve read, PMSA PET-CT is extremely precise and appears to provide some of the most convincing evidence of prostate cancer spread.

I would not hesitate to get one if my doctor believed there was a significant possibility to expect my cancer to have spread.

All the best.

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