I tested out as Chronic Kidney Disease stage 3 (the worst being stage 5). Fortunately after stopping omeprazole my kidney value went up enough to barely make it back into the reference range, meaning I suffered an acute kidney injury instead of remaining in a chronic stage. Who knows if that would have been possible if I hadn't stopped the PPI when I did. I supposed I was more dramatic about it than I needed to be but when the DX first came down and I went to a hospital presentation on CKD I was devastated. Even with the improvement I live in fear that the kidney values will go down again into the CKD range, since they are so close to the line now. That designation also has health insurance implications

My lowest T score from the DEXA scan is -3.8, which my doctor called severe, a score more appropriate for someone 20 years older than I. The other vertebrae were in the -3 range too (-2.5 is the defining line for osteoporosis).

I am also deficient in B12, which is a common deficiency with PPIs from what I read.

I now am trying to eat better to support my kidneys and bones, and doing weight training for the bones too.

Not everyone gets side effects, but I switched doctors after I found out about the kidney/bone issues. The new doctor told me that in general people shouldn't take PPIs long term because of side effects and she preferred first addressing gerd with diet and lifestyle changes. If nothing else, people on long-term PPIs should monitor for these issues so they can find out quickly if they have side effects. Most people don't have these problems but if they happen to you, it can be life-changing.