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Signatera Test. Is it truly helpful and worthwhile?
Breast Cancer | Last Active: Nov 30 12:06pm | Replies (60)Comment receiving replies
The way I understood it (and I may be incorrect) was that the test checks for circulating damaged DNA specific to tumor biology. So, if it is checking for damaged cells from my ER+PR+HER2- tumor, I am thinking it would not recognize DNA from a new tumor with different biology. Does anyone know if that is correct? I am having these test every three to four months. So far everything has been negative.
Replies to "The way I understood it (and I may be incorrect) was that the test checks for..."
That is correct. The test is focused on the analysis of the DNA of the actual tumor tissue they received
It does not detect a new tumor, it only detects recurrence with matching circulating tumor DNA of your original tumor.
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I really don't know much about it but have read enough to know that I would like to have these blood tests done myself. Does insurance cover this?