I am so torn about this. I'm scared to reinstate a big dose of Effexor, even 12.5mg because the next weaning off would be my third time, and could be bad. I've reinstated 2mg for 7 days and 4mg for 2 more days. No change. I'm so scared of Effexor now, I think I will try Prozac. At least it comes in liquid form. Micro-tapering Effexor is hard. My tiniest bead is 0.4mg which is a lot. People go two decimal places with tapers when they can.