Hi, yes I took the big 3 antibiotics including the Amikacin. Well it will affect your hearing and tinnitus as in my case. At times the ringing was too loud that I had to stop and take a break for the day and restart the next day. Every body is different and overall I felt like light headache every single day and developed cramps in my stomach. But after few days your body will adjust and things will improve..good luck!