Riding __may__ raise the PSA in a patient with a prostate. I would think it would have no effect on him.
Congratulations to both of you on kicking cancer's ass!

I was told by my one oncologist, not to ride my bike 24 hrs prior to taking my PSA test. Never found out why. I still practice this advice. I’m on my second recurrence. So go figure 🤷‍♂️

Biking can raise the PSA due to the pressure on the pelvic area (where the prostate is.) So can sex. In both cases, it's probably more likely with extensive vigorous activity than more limited casual activity, but who really knows. It's just an association. If there were more cowboys, we might know that hard riding of horses had a similar association?! Pole dancing? Gymnastic pommel horse? Anyway, you get the drift.
Without the prostate, there is less PSA, but also less data. Who really knows if biking has any effect. If you did a long bike ride and got a higher PSA, you could always retest without the biking or other strenuous activities involving the pelvic area and see if it's lower. Or vice versa.
I suppose if you want to minimize PSA "shedding," you could spend a couple days laying in bed or on the beach?! before each PSA test. I kind of like that. A "medically necessary" couple days laying on the beach or by the pool. I definitely think you should do this with your husband @jwoy . You heard it here, on this unauthoritative forum. It might also lower blood pressure?!

I bike a lot, 5000 miles a year, on the road, gravel, dirt, home trainer. When I had a prostate, I avoided biking for 48-72 hours before PSA test. Now after removal, I no longer think about the timing of the test in relation to bike rides. All tests after surgery in April this year are undetectable.

The prostate is located in the space which rests on a bike saddle. One study showed a rise in PSA in men who rode within 2 days before a test. Other studies have not shown a correlation. The theory is, pressure on the prostate causes the increased release of the PS antigen. Without a prostate, I don't see why biking should affect the PSA results.

I see the other post addressing this. This recommendation for not bike riding prior to PSA test is for those who have a prostrate. Riding a bike can irritate the prostrate and cause a rise in PSA test.

If your husband had his prostrate removed there is nothing to irritate the prostrate as there is not one. But he had surgery to remove it so ask if riding a bike could irritate the surgery. This would not affect the PSA but could affect the recovery of his surgery.

I was a long distance bike rider (25 miles) and was already told not to ride by PCP prior to my PSA tests even before my radiation treatments and follow up PSA tests.

We have quite a few cyclists in the Prostate Cancer Support Group. Here are few related discussions:

- Post Prostatectomy Incontinence: When can I start bicycling again?
https://connect.mayoclinic.org/discussion/post-prostatectomy-incontinence-bicycling/
- PSA test and bike riding after Prostatectomy
https://connect.mayoclinic.org/discussion/psa-test-and-bike-riding-after-prostatectomy/
- Cycling after radical prostatectomy (RP)? Increase risk of recurrence?
https://connect.mayoclinic.org/discussion/cycling-after-rp/

I still have a prostate (radiated), and am keeping my PSA < 0.01 with Firmagon and Erleada. I saw no change in the result when I was cycling in the spring or summer, but I can't remember if I'd cycled within 72 hours of getting my blood drawn.