Seasuite, Yes PSA levels vary greatly between people PRIOR to treatment. Mine went from 1.3 to 3.6 in a year and at 72 years old that was well within a "normal" range. I explained to my urologist that there was a family history of prostate cancer (grandfather, father), he still suspected BPH but scheduled an MRI anyway just to be sure. The results came back Stage 4 with mets to my pelvis. ADT and radiation was started almost immediately and PSA dropped to undetectable. My urologist said most of his patients in my condition would have had a PSA well over 20. After radiation or surgery, and after ADT is finished, PSA becomes a very ACCURATE and reliable indication of whether the cancer is still there. For folks like us, PSA velocity (rise in level over a years time) is more important than actual PSA levels.