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Polymyalgia Rheumatica (PMR) | Last Active: Dec 6, 2023 | Replies (21)
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The biologic that targeted PMR was Actemra (tocilizumab) and it worked for me.
Another biologic was tried. It was thought to be "optimal" for uveitis. It was called Humira but it didn't seem to work for PMR.
A biologic that is now FDA approved for PMR is called Kevzara.
Replies to "The biologic that targeted PMR was Actemra (tocilizumab) and it worked for me. Another biologic was..."
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This is fascinating to me. I began my treatment with Humira and methotrexate and it worked until the mtx caused elevated liver enzymes. When we reduced mtx, I developed antibodies to Humira and had to switch to Enbrel. That worked well for 2 yrs and then it didn’t. So I was switched to Remicade infusions and they are still working well.
Today there a lot of biologic options for RA. It’s curious that a condition so closely related isn’t relieved by them.
I try to power through flares because I want to reserve prednisone for urgent situations. Thankfully they’re uncommon for me. But when they come I watch it unfold from distal joints to more proximal and larger ones and in 10-14 days it’s usually done.