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What comes after Evenity?

Osteoporosis & Bone Health | Last Active: 4 days ago | Replies (42)

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@windyshores

@mayblin what an interesting idea! The liquid version of Fosamax...

I have been told that Reclast is much more potent. After the 20% test dose, I am supposed to tell my doc what dose I want after a month of evaluating tolerability, and that second dose would be three months after the first. I have read that a half dose is as effective as full dose (sorry can't cite right now).

Keith McCormick thinks I could do a 20% dose every three months.

I am going to look into this idea of a liquid form of Fosamax. I wonder if, chased with water, it would pass through quickly enough to avoid affecting the esophagus. Or maybe the liquid will coat the lining and be worse than a pill that passes through. At any rate, thanks for the idea!

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Replies to "@mayblin what an interesting idea! The liquid version of Fosamax... I have been told that Reclast..."

I'm trying to figure out what to do after my forteo, maybe I will have another year of it. If not, and if fosamax liquid form is a viable choice for me, then I'd have 2 bisphosphonates to choose from.

If I remembered correctly, the solution of fosamax (100ml) is followed by 60ml of water (compare to 240cc of water for tablet form), so esophagus shoud be clear of meds quickly. Your thought of liquid medicine may have actually give the active ingrient a chance to have closer contact with stomach lining is a good point. If this is not a concerning issue, then liquid generally have a lot faster gastric emptying time than any solid or semi solids hence a less gi irritation. Finding gi side effects rates in liquid vs tablets may give a clue.

@mayblin
Hi, who is Keith McCormack? Is he published anywhere? It sounds like you will explore liquid Fosamax, not Prolia & Reclast…I’m very interested in any alternatives too…. I get consults from 2 Endocrinologists but they both lean only to the 2 common follow ups. I asked what if you’re allergic as it lasts a year…she mentioned some minor ones ..take typical etc.are there rational docs we can get that will be open?. How do we get them..no one seems to want to try anything else.any advice with how you did it would be most welcome!.