Fosamax and depression

@lori5548 I took Fosamax for 5 years and I have a history of anxiety and depression. I did not notice any changes - an upswing in depression and/or anxiety - while I was on Fosamax. I take duloxetine (Cymbalta), 20mg/day, which is a low dose and it works for me.

Fosamax has been around a long time and so side effects, when they occur, should be well known. Have you talked with your prescribing doctor?

Thanks Helen. I take cymbalta as well. I took 20 mg every other day for years and now take it every day. I have not talked to my provider. I keep thinking I will go back to my normal. I do see a psychiatrist ever 3 months and will mention at my next appointment. Thanks for sharing your experience.
Lori

Lori, though these side effects were not signaled in the clinical trials, there is subsequent reportage from patients.
Some times adverse symptoms lessen as your body adjusts, but because you've been on Fosamax (alendronate) for three months it is more likely that whatever is in the medication that bothers you, it is building up.
You could check to see if there are interactions with any other medication you are taking. In your situation I would stop the Fosamax and call my medical provider. It may take several weeks for the symptoms to subside.
It is brave to continue a medication that is troublesome, but is it wise?

"The osteoporosis drug alendronate increases the risk for depression more than 14-fold in people aged 65 years and younger, and more than 4-fold in people aged 65 years and older.Feb 17, 2022"

Lori, though these side effects were not signaled in the clinical trials, there is subsequent reportage from patients.
Some times adverse symptoms lessen as your body adjusts, but because you've been on Fosamax (alendronate) for three months it is more likely that whatever is in the medication that bothers you, it is building up.
You could check to see if there are interactions with any other medication you are taking. In your situation I would stop the Fosamax and call my medical provider. It may take several weeks for the symptoms to subside.
It is brave to continue a medication that is troublesome, but is it wise?

"The osteoporosis drug alendronate increases the risk for depression more than 14-fold in people aged 65 years and younger, and more than 4-fold in people aged 65 years and older.Feb 17, 2022"

@lori5548 Interesting, isn't it, that we take the same antidepressant.? Yes, it's something to talk about at your next appointment with your psychiatrist as they would know best what medications might contribute to depression and anxiety.

Lori, though these side effects were not signaled in the clinical trials, there is subsequent reportage from patients.
Some times adverse symptoms lessen as your body adjusts, but because you've been on Fosamax (alendronate) for three months it is more likely that whatever is in the medication that bothers you, it is building up.
You could check to see if there are interactions with any other medication you are taking. In your situation I would stop the Fosamax and call my medical provider. It may take several weeks for the symptoms to subside.
It is brave to continue a medication that is troublesome, but is it wise?

"The osteoporosis drug alendronate increases the risk for depression more than 14-fold in people aged 65 years and younger, and more than 4-fold in people aged 65 years and older.Feb 17, 2022"