← Return to What comes after Evenity?

Discussion

What comes after Evenity?

Osteoporosis & Bone Health | Last Active: 4 days ago | Replies (42)

Comment receiving replies
@mayblin

@windyshores I just send a reply message to you under 'undecided choice of drug for op'.. Sorry I didn't do a thorough reading though different treads. Now I'm seeing you are on evenity after tymlos, and planning on a reduced dose of reclast, right?

The main purpose of this writing is in regards of bisphosphate usage after an anabolic, in your case is after anabolic and evenity. Like you, I have gerd, a mild one and asymptomatic. Upon reading the classic fosamax, I realized that fosamax has a liquid dosage form. It seemed stomach irritations are mainly due to the lining in direct contact of broken down particles, or actice ingredients of fosamax tablets. Some reports indicate that might be why some generic fosamax may cause more irritation because of the differences in disintegrating rate compared to the brand. My thinking is solution 'form' might be the solution! If the transient time in stomach is markedly reduced with the solution form, would that be usable for pts with gerd or stomach issues? I'm yet to do more readings regarding the bioequevalency of the solution since it's available only as a generic. My thinking is that a gentler bisphosphanate might not 'lock in' all the gains of an anabolic, but it might be a better candidate should future repeated anabolic usage is needed. Does this train of thought has any merit? Whats your knowledge about ' lock in' agents after an anabolic? Thank you very much!

Jump to this post


Replies to "@windyshores I just send a reply message to you under 'undecided choice of drug for op'....."

@mayblin what an interesting idea! The liquid version of Fosamax...

I have been told that Reclast is much more potent. After the 20% test dose, I am supposed to tell my doc what dose I want after a month of evaluating tolerability, and that second dose would be three months after the first. I have read that a half dose is as effective as full dose (sorry can't cite right now).

Keith McCormick thinks I could do a 20% dose every three months.

I am going to look into this idea of a liquid form of Fosamax. I wonder if, chased with water, it would pass through quickly enough to avoid affecting the esophagus. Or maybe the liquid will coat the lining and be worse than a pill that passes through. At any rate, thanks for the idea!