Has anyone ever suggested that you might have more than PMR going on? Methotrexate worked reasonably well for me too. It worked for me as a "steroid sparer." Unfortunately when I spared too much prednisone all hell broke loose like you say. The hell was worse than PMR only.

I have a variety of autoimmune conditions. My rheumatologist said the folloing referring to my treatment plan, "One medication works for one thing and another medication works for another thing." Unfortunately, I couldn't tolerate or she could not prescribe both medications together. Then the following conclusion was added, "It would be impossible to adequately treat everything"

My rheumatologist stopped methotrexate "due to infections" not because it wasn't working.

I did have a massive flare of something when Actemra controlled PMR. It wasn't GCA. My ophthalmologist still doesn't believe Actemra is optimal for the condition she is worried about more than PMR. My ophthalmologist says I should be on a TNF-inhibitor except it doesn't work well for PMR. I can't have two different biologics ... I can only have one or the other but not both.