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Treatment for Prostate Cancer Metastasized to Bones

Prostate Cancer | Last Active: Feb 27 7:27am | Replies (146)

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@northoftheborder

I think that's a little harsh, and unnecessarily discouraging for people with newly-diagnosed bone-metastatic prostate cancer. It really depends on the number of metastases, and even then, there's huge benefit from introducing androgen-reception inhibitors like Apalutamide. I'm at 26 months now, with PSA still undetectable (< 0.01) — tested today — and no progression. I had the metastasis in my spine radiated, as well as the primary tumour in my prostate.

The TITAN study for metastatic, castrate-sensitive prostate cancer (using ADT and Apalutamide) did not even reach median overall survival at 52.2 months. Median overall survival with ADT and placebo was still almost 40 months.

Source: https://ascopubs.org/doi/abs/10.1200/JCO.2021.39.6_suppl.11

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Replies to "I think that's a little harsh, and unnecessarily discouraging for people with newly-diagnosed bone-metastatic prostate cancer...."

North…. I have been on a clinical trial with Erleada and lupron and had those drugs for 13 months with surgery after the 6 th month. I am now 24 months since beginning g the trial. I understood that in this trial event free survival would be approximately 41 months and survival would be not more than 66 months. Did I misunderstand the results of this trial?