← Return to Mixed results 1 year after Forteo: What are your thoughts?

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@mayblin

I might have been too eager to give my hip/femor a "load" after seeing the concerning results. Hope I didn't inadvertently damage any parts of my knees, which my strength training coach kept telling us to protect. I'm backing off from the higher impact ones for now. As far as protein goes, I'm uping to 90grams per day from 75. Yes quality and quantity matter yet opinion differs. Hopefully the amount of protein will help me build more muscle mass. I also don't mind having extra adipose tissue as long as they don't all go to my tummy, that might be a tall order.

gently, whats your strategy to get enough calcium?

I don't know much about the anatomy of the bones. Looking at the part where the tech took dexa scan of the femoral bones (the neck), they looks like a trabacular part of the cortical bone, ie, porous part. Am i right? If theoretically the newer made bones by forteo are more porous hence less dense, then would L spine be the same? Mccormick did mention he has seen the wrist bones, which are made of 80-90% dense cortical bones, suffer a decline in bmd after forteo. I'm not too fazed yet since my hips/femur started at ~1.8 which gave me a bit wiggle room. If the speed of the trend continues, then I may regret my decisiom of jumping on the rx bandwagon too early.

If I understand your general strategy correctly, you will be using CTX &P1NP level to exit Forteo? Do the level of these bone markers correlate well to state of bone building vs resorption? Will you do a DEXA at the same time too? Forteo then Forsamax I understand, but whats the rational behind Forteo (i assume followed by a holiday) then Forteo?

Also my impression is that sources of your trust prefer fosamax over reclast. Is this due to their stickiness to the bones? I read fosamax could also stick to bones very long up to 10 years, but I need to read more about this. My doctor is planning reclast for me for 1-2 years after forteo. Now I'm open to reclast, fosamax (I'm searching for a way to get around of the stomach issue since I have mild gerd) . HRT is also on the table since it's a natural way to inhibit osteoclast. But right now i know nothing about hrt. Bisphosphalated bones concern me as well.

The longer term picture (say 10-20years from the start of 1st therapy) is also very uncertain. I felt if we are lucky, maybe we could get bmd to -2 to -2.5 even a bit worse and safely get off the last drug and maintain what we've got just via healthy eating and exercise. If not, a well calculated plan such as anabolic to bis, then maybe back to anabolic... this maybe doable, but for how long? Evenity is an interesting consideration, it seems to be a 'perfect' drug on paper if it mimic real life bone remodeling process. The big question also is, then what?

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Replies to "I might have been too eager to give my hip/femor a "load" after seeing the concerning..."

mayblin, my strategy with calcium is not recommended even by me. While I'm meticulous about protein. My (mis)take on calcium is that calcium is not the problem. Still, I have rules (for myself). I take 250mg before Forteo. I never take calcium without taking K2 two hours before. I never take more than 250 mg at a digestible time. I've read that we can't absorb more than 500mg at a time. But I larger people must have more villi than I do. I don't want any of that calcium heading to my arteries.
It is considered by many that excess calcium from supplementation is a partial cause of athersclerosis. There are many who discount the connection. I also take 250mg at night because we lose calcium overnight according to an amazing bone expert who suggested the final dose of the day.
If I were counting milligrams of calcium I wouldn't count the calcium in dairy because calcium lactate is the least absorbable form. I do drink ultrafiltrated milk mostly to avoid the sugers in milk. Fairlife 380mg of uncounted calcium per cup.
I think you can get enough calcium through a good diet, which is why I have osteoporosis.
I fully recommend Fairlife non fat milk and Citrical if you break the 500minis in half.
I think estrogen is the problem
Too many Is in this comment.

My Endocrinologist told me that Fosamax locks in the bone increase. Without it you will loose the Forteo bone density increase.

I will stop Forteo on July 21,2024. At that time I need to have a Reclast infusion to hold any bone gains in place. My oral surgeon would prefer me to take Fosomax instead of Reclast, because of complications with the jaw bone should I need invasive dental work in the future. Are there any studies comparing the efficacy of Reclast vs Fosomax in holding bone gains after Forteo?