Damage from Iovera Nerve block prior to TKR

Posted by kathi65 @kathi65, Nov 8, 2022

I had right TKR 18 weeks ago. Prior to surgery I had lower leg neuropathy and a neurologist could not determine why after testing (you're part of the 20% of the population that gets it for an unknown reason she said). My surgeon recommended the Iovera nerve block prior to surgery because it would help with pain after the surgery. He said that the nerve block would last for about 3 months. I had no problem when the injection was done, minimal bruising and my leg was numb. It's now been more than 3 months later and I still have numbness going all the way down the inside of my thigh to my knee and when I touched the skin it feels like someone's taking a razor blade and slicing my skin open. I'm also having problems when I bend my leg in certain ways or touch my leg in certain spots I start get sharp nerve pains down on my lower leg. I don't know if this is from the Iovera injection or not. And I have a feeling nobody's really going to tell me. Has this happened to anybody else? I already had a chronic pain condition before surgery and if I had known that I would feel the way I do now I don't think I would have had my knee replaced!

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I had a TKR in August 2023. At 6 weeks I am feeling what feels like acid going along my nerves. It started out as lightning and has progressed. I was told it would last 3 to 4 months.
I have a band along the right side of my knee and one over the top that feels as though it's a rubber band stretched to the breaking point. I don't know if any of this is caused by the shot or not.

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My partial right knee replacement was 3 months ago. The iovera was done 16 days prior to the surgery. My pain increased from the day it was done. I have done a wheel chair, PT, walker, cane. I can walk but not without pain in two places. Of course, it still hurts inside my kneecap where the new metal knee was placed. But there is an arc shaped band of muscle above my knee that is stiff and resistant to movement. For example, it is terrible painful and difficult to get up from a sitting position, including the toilet! A lot of PT time was spent on this problem, and I learned a way to hoist myself up, but very painfully. I still have a lot of stretches and bends that put weight and pressure in this area and it still hurts every time. Like the rest of you, I would never have allowed the iovera if I had known. By contrast, I broke my left knee a year before the right knee replacement and my recovery WITHOUT IOVERA was much less painful and much more complete. I hope I will be able to move better after the iovera wears off. My sympathy for all of you who had it too.

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@ziggy1

I had a TKR in August 2023. At 6 weeks I am feeling what feels like acid going along my nerves. It started out as lightning and has progressed. I was told it would last 3 to 4 months.
I have a band along the right side of my knee and one over the top that feels as though it's a rubber band stretched to the breaking point. I don't know if any of this is caused by the shot or not.

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I would say that you are experiencing nerve pain. Those lightning types sensations you describe are similar to what I had. The only relief I got was by taking a medication called Lyrica. Is specific for nerve pain. Unfortunately, regardless how skilled the surgeon might be some of us have more damaged, nerved than others, and end up having to deal with this type of pain.
Be patient. It will get better. Recovery takes about a year. (Which is much longer than I ever expected)

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@continentalred

I would say that you are experiencing nerve pain. Those lightning types sensations you describe are similar to what I had. The only relief I got was by taking a medication called Lyrica. Is specific for nerve pain. Unfortunately, regardless how skilled the surgeon might be some of us have more damaged, nerved than others, and end up having to deal with this type of pain.
Be patient. It will get better. Recovery takes about a year. (Which is much longer than I ever expected)

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I've had both knees replaced with success. I feel terrible for those of you who have posted here and are in so much pain/discomfort.

I am familiar with Lyrica and I do believe it works well for nerve pain. As for numbness, as one writer noted, surgeons have a hard time avoiding this due to the extent of the surgery and that nerves are all over the place. I had numbness on the skin over both knees and inside the knees. It lasted for about six months and has mostly resolved.

I hope you all find relief and I'm sorry I don't have more to offer. As for exercise causing pain, that should be stopped. Therapy after surgery causes a lot of discomfort but not sharp pain. that should be looked into. My only other suggestion is to ice the affected areas as much as possible and use OTC pain relievers like Tylenol. Above all stay as active as possible, given the pain, to avoid the development of scar tissue.

I wish the best to all of you, and again, I'm terribly sorry for what you're going through. It's hard to have patience, but sometimes a lot of these things resolve within a year, or at least get better. It's a common but very invasive surgery. You are all very courageous.

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I had Iovera two weeks before my TKR. I got sharp stabbing nerve pains and now it’s even worse. I had surgery two days ago. The surgeon doesn’t want to hear about it. It’s a relentless sharp nerve pain. I don’t think it worked at all

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So, do I understand you correctly that you had nerve problems before you got the IOVERA therapy?
I am having TKR in February and am scheduled to have the IOVERA therapy two weeks before that.
I am concerned about the long term effects of having that treatment, but was told of no such issues.
Does anyone else out there have any comments about IOVERA therapy and it's possible side or long term effects?
Thank you.

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@josephinecarrion

I have a very bad right knee with torn meniscus etc. and I need a knee replacement. I was trying to hold off on it for a few years so I went to my doctor and he recommended this procedure. I can’t begin to tell you what kind of pain I’ve been in since the day he did it. My pain now is worse than before. I don’t know what to do. and I called the doctor and I got no explanation about this from him other than take Tylenol. Meanwhile, my whole entire knee is not only numb but I feel like somebody put a knife in and never took it out.

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My pain after the injections is also worse. I have no idea why or what to do about it.

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@rae1954

My pain after the injections is also worse. I have no idea why or what to do about it.

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There’s not much you can do. Give yourself about one month and a half and the pain will come down. My doctor gave me gabapentin, but I only took it one day or two. It didn’t help. I don’t like taking too many pills when I don’t need them.

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@josephinecarrion

There’s not much you can do. Give yourself about one month and a half and the pain will come down. My doctor gave me gabapentin, but I only took it one day or two. It didn’t help. I don’t like taking too many pills when I don’t need them.

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That’s depressing

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I received my IOVERA treatment on Thursday, January 25, 2024. I had to have three locals because my nerves were over sensitive to the injections, but immediately afterwards I had no pain in my knee at all. I am hoping that the treatment will work as well as promised after my TKR. I know there will be join pain, but PT shouldn't be nearly as painful as it would be without this therapy. I am a little concerned about long term effects, but have been told there shouldn't be any. I'll let you know.

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