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Signatera Test. Is it truly helpful and worthwhile?
Breast Cancer | Last Active: Oct 2 6:42am | Replies (56)Comment receiving replies
I’m a Signatera client. Company is Natera . They Obtain a sample of BC tumor or node and draw blood done at oncology appointment. Within a few weeks they analyze the tissue and establish a DNA profile. Blood draw every 6 or 3 mos. In onco office or phlebotomist sent to your home by the company… free of charge… The blood is analyzed for circulating DNA (ctDNA) related to your tumor. I have had 3 … thankfully NEGATIVE… draws/results.
If positive it may represent 12-18 mos before a scan would detect . That is the reluctance of use… how to treat?
My oncologist would schedule a PET AND likely prescribe a medication like Verzenio , Kisquali or Ibrance which have long been used in Mets arena and now being used in primary treatment in non metastatic arena.
It’s comforting to get a negative result … but adds stress awaiting result.
It’s definitely the wave of the future.🌸
Replies to "I’m a Signatera client. Company is Natera . They Obtain a sample of BC tumor or..."
Thanks for sharing and it sounds like your oncologist is on board! My oncologist at Dana Farber here in Boston was not and it's disappointing some docs don't want to use some of these new tools as early detection is still all we have. How difficult is it to get a sample of my tumor as I had a lumpectomy for invasive lobular in Nov 2022. I doubt Dana Farber would let me use their lab for the blood work up. Any intel appreciated!xoxo
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@anjalima Thanks for sharing! I’m in Canada and not impressed so far by the process. Any tips on finding a US doctor who supports Signatera? Obv I would have to pay out of pocket. Thank you! Terrified of recurrence if I can make it through this first round (stage 1, lumpectomy so far, ++ -, 38 yo).