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DiscussionSignatera Test. Is it truly helpful and worthwhile?
Breast Cancer | Last Active: Apr 28 11:57am | Replies (123)Comment receiving replies
Replies to "What is the cost of the signatera test for those without Medicare or other insurance ?"
Self pay is $395.00
CPT codes from Natera 81479 and 0340U
to give to Medicare show no
coverage.
@pbnew
I had my first Signatera test in Feb this year, 2026. The cost is sliding scale in a sense and the qualification for price reduction is very generous (youvcan have a fairly high income) but it was hard prying the info and the reduction from them. They all eagerly wanted to help but it just took a lot of back and forth and them not knowing their own criteria. So keep at it. They said almost everyone pays $0 however i am paying $249 instead of the full $500 for each test and they recommend having this blood test every three months. It was not covered by Medicare or my insurance. So. My household adjusted income on tax return is about $70k.
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Call Natera and they will be able to answer this. My “ understanding “ is that they are not charging right now pre FDA… development of data stage.