← Return to PMR flare at a drop from 8 to 7 mg of prednisone?

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PMR flare at a drop from 8 to 7 mg of prednisone?

Polymyalgia Rheumatica (PMR) | Last Active: Dec 2, 2023 | Replies (44)
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@barracudacool

I saw my doc yesterday, I am back up to 20mg of prednisone after being down to 7. My doc is now taking me off of methotrexate and putting me on Kevzara which is pretty new for pmr but he said “well you are just one of those people who don’t taper gracefully.” It looks like it might be a good fit for me.

https://www.kevzara.com/

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DadCue | @dadcue | Dec 1, 2023

Not being able to taper gracefully is a good way to describe it. There was nothing graceful about how I tapered---that's for sure.

Kevzara (sarilumab) was FDA approved for PMR in February of this year---2023.
https://www.the-rheumatologist.org/article/fda-approves-sarilumab-for-the-treatment-of-adults-with-glucocorticoid-resistant-pmr/#:~:text=On%20Feb
and
https://www.ajmc.com/view/sarilumab-indication-expanded-to-include-polymyalgia-rheumatica
I hope Kevzara works for you.

Actemra (tocilizumab) helped me taper off prednisone gracefully. Actemra is FDA approved for GCA.

Kevzara and Actemra target the same inflammation pathway.

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