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@stevm

I am also starting this same regimen on December 11. Just completed 12 cycles of FOLFOX. Came through relatively unscathed. Neuropathy seems to be the only lingering side effect. Scans are clean and CA-19 numbers have been consistently under 10 since the start of chemo. Tumor was removed prior to treatment. Had a distal pancreatectomy and splenectomy. Would be curious to know if chemo/radiation will make the neuropathy worse.

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Replies to "I am also starting this same regimen on December 11. Just completed 12 cycles of FOLFOX...."

I developed mild peripheral neuropathy in mid-Oct., which was about 2.5 mos. after my final (8th) infusion of FOLFIRINOX and about 2 weeks after my Whipple.

I'll let you know whether this combo affects my p.n. Best wishes.

Hello stevm,
I wish you luck in your treatment. My case was similar to yours as I was a distal, stage 2, 12 rounds of chemo; marker at 6. My surgeon thought I would go on the oral chemo, but my oncologist looked shocked when I told her. She said the usual mantra “your margins are clear and your antigen low” and said no reason for it. Now I understand that may not mean much right after chemo. My genetics like most is the KRAS g12-d. Dr never explained what that meant and only after chemo did I look it up and then understand why longevity can be a challenge with this disease without the right treatment. I take it you were a stage 2? May I ask which facility you received your care? I applaud your drs for taking that extra step of insurance in fighting this disease and wish you well.