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← Return to PN from low dose b6
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So, John, IF I am interpreting the medical jargon correctly, P5P is less likely to cause B6 Toxicity than Pyridoxine? My podiatrist put me on Metanx a month ago, and I was concerned since I saw that it contained B6 and I had read so much about B6 toxicity causing neuropathy. But I had just had my B6 plasma levels checked by my PCP and my B6 was at a very good spot. So I have been taking the Metanx, and it "seems" to be gradually making a difference. I understand it may take up to 3 months to feel the full effect. In the meantime, I am planning to have my B6 level re-checked after a few months.... just to reassure myself. This disorder is so complicated and each of us may react differently to the treatments offered ... with some, sadly, having no reaction at all. Thank you for sharing this information!! I am SO glad that I found this group! Mike
Replies to "So, John, IF I am interpreting the medical jargon correctly, P5P is less likely to cause..."
Hi Mike, My takeaway from reading the article was that the P5P is more readily absorbed and used by the body up to 10 times more, if I remember correctly, than the regular vitamin B6. That's great news that the Metanx seems to be helping. Looking forward to more updates of progress for you.
Hi, Mike
Insanely, perhaps, I see two different neurologists in two different clinics, miles apart. The one neurologist is the one who suggested I try the EB-N5, and who consulted with about my B6 concerns, putting my concerns to rest. Then a few weeks ago, I had a routine follow-up with the other neurologist and, naturally, I brought up the question of B6 and toxicity. She ordered fresh labs.
(By the way, each neurologist knows I see the other; they're friendly colleagues.)
The labs came back showing my B6 as HIGH: 99.4 against a reference range of 3.4–65.2. With the blessing of both doctors, I'm currently doing a six-week "experiment": cutting my daily EB-N5 dosage in half, after which I'll get more labs.
A side note to all this: I'm five months into using EB-N5. Recently, my PN symptoms "seem" to have lessened. Have they? Or is it just wishful thinking? My mentioning this here is the first and only time I've mentioned it. I'm not telling friends, not even my partner, for fear of jinxing a good thing. 😀
Ray
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Mike, glad to hear this seems to be helping. Let us know what symptoms you see improving as the months go by. Best wishes.