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Do ALL men get side effects from Lupron shots?

Prostate Cancer | Last Active: Dec 3, 2023 | Replies (28)

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@kujhawk1978

I did Lupron for 18 months.

Side affects I experienced:

Mild fatigue
Mind muscle and joint stiffness
Mild to moderate hot flashes
Weight gain -10 pounds
Genitalia shrinkage

I did not experience depression or loss of libido (much to my wife's dismay...)

Think of statistics, Bell Curve...

The manufacturer's web site lists all the possible side effects, question us, which one will you experience?

You can mitigate the side affects through diet and exercise,

There are also metabolic and cardio vascular side effects so have a cardiologist on your medical team and check cholesterol, blood pressure....

Finally, if you are going to be on Lupron for an extended time have a baseline bone density test and talk with your medical team about supplements such a Vitamin D, Calcium, Magnesium.

Kevin

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Replies to "I did Lupron for 18 months. Side affects I experienced: Mild fatigue Mind muscle and joint..."

Kevin, you summed it up perfectly for what I have experienced. My last Eligard injection was June 19, 2023 and the duration of its effects is supposed to last for 6 months which will be the 18 months of treatment the urologist wanted. I began 3 months before starting 39 sessions of Proton Beam therapy at MD Anderson. My question to you is when did you first notice the lessening of the hot flashes and night sweats of the 18 months of Lupron? I am assuming you had 3 injections spaced 6 months apart? The weight gain, (about 15 lbs.) and the day and night sweats have been the most bothersome of the side effects. Shrinkage and loss of libido, while on ADT is an effect, but I have not been bothered by it psychologically.