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Neuropathy | Last Active: Jun 13 6:09am | Replies (111)

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@johnbishop

Ed @njed, I take 1200 mg daily (600 mg morning and evening) of na-R-ALA which is a better form of R-ALA. I'm not sure the ALA is helpful since most sold as ALA contains 50% synthetic ALA (s-ALA) which is not as bioavailable as R-ALA or na-R-ALA. The labels should show the content of the s-ALA on the bottle when the product is labelled ALA. Then na-R-ALA is just one of the supplements I take for the neuropathy. The full list is in the Protocol 525 discussion here - https://connect.mayoclinic.org/discussion/have-you-tried-the-new-protocol-525-product-for-neuropathy-relief/. The supplement is no longer called the Protocol 525 since they've reduced the number of capsules to 4 in the morning, 2 at noon and 4 in the evening.

Here are a few reference articles on R-ALA on the topic.

--- (R)-Lipoic Acid: Unique ‘Mitochondrial Antioxidant’ Fights Premature Aging: https://nutritionreview.org/2019/07/r-lipoic-acid-unique-mitochondrial-antioxidant-fights-premature-aging/
--- Analysis of the Enhanced Stability of R(+)-Alpha Lipoic Acid by the Complex Formation with Cyclodextrins: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723188/

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Replies to "Ed @njed, I take 1200 mg daily (600 mg morning and evening) of na-R-ALA which is..."

John - thanks for the info you provided. I will check out the links you provided. Many of us rely on you and the other mentors for information and I can't tell you how much I've learned about PN just from the knowledge you and others have to share with us. Very much appreciated. I definitely want to know more about the R-ALA. Again, John, thanks.