I started with Actemra injections every 2 weeks ... that was 4 years ago. I got off prednisone for a while but I flared and needed 60 mg of prednisone again.

Actemra made it possible to taper off prednisone the first time so I requested to be on Actemra again. My rheumatologist agreed but said I should do weekly injections instead of every 2 weeks.

Weekly injections worked well and I got off prednisone a second time. Eventually I "progressed" to monthly infusions. I have been doing monthly infusions for about a year and I think the infusions work extremely well.

After 4 years of either Actemra injections or infusions ... my rheumatologist thought it was time to stretch the interval between infusions to every 5 weeks instead of every 4 weeks.

Infusions every 5 weeks have been good. I don't know what the next step will be. I'm willing to go 2 months between infusions.

I believe that I will never know unless I try it and see.