Rifampin made me very sick, I had aggressive, endless diarrhea, stomach cramps, and zero appetite. At the time, I had no idea which drug was causing this, and I just sucked it up. But I read a lot about Rifampin and how it made other people sick. I was going away and I could not have the diarrhea on the flight, so I decided to stop taking the drug for the duration of my vacation. The diarrhea was soon gone and I regained my appetite. I told my pulmo, and begged her to take me off rifampin.