That is one nasty drug. I took it for over 13 months with the other two and for some reason developed a reaction to it. It put me in the hospital twice this year. After the second time with elevated heart rate of 150 and oxygen level dropping to 77 and a four day stay at hospital, I took my self off all of the drugs. I will never ever go back to the I.D. doctor again. I tried to tell him and he wouldn't listen. He almost killed me. I informed my Pulmonary Doctor, that he was in charge, because I wouldn't go back to that I.D. doctor again. It is well documented the side effect of the drug and the I.D. doctor should have known better.