Connection between Neuropathy and L4,L5 Issues

Posted by seidholz @seidholz, Oct 29, 2023

I have been diagnosed with idiopathic PN by multiple Neurologists at Mayo, UNMC and Northwestern- the numbness runs from my knees to my feet with only occasional burning however it affects my balance and comfort.
I have also been diagnosed with degeneration of my L4 and L5 on my right side after years of intense physical activity led to 2 hip replacements.
I have started to notice that my PN becomes somewhat asymmetrical after certain core workouts I do to strengthen my core… is it possible that the L4/L5 issues are causing me to pinch nerves leading to my PN?
BTW- I was very happy with all of my doctors at each facility. Mayo in particular
Dr Dyke is fabulous

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@seidholz

One under the back of the knee and the other on the top of the foot

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Thanks…..

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Have foot Dr. Called it Neuropathy around 2000 . I have had pain every day since. from knee to bottom of my feet. no Dr wants to talk about it. VA has turned me down 3 times, a says I should have started when within 2 years after leaving SV (agent Orange) Have started over again for VA disability.

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@penn - I hear about situations like yours and I realize that surgery is absolutely the last item to consider and has to be done with all known facts. I am not a candidate for surgery. I'm sorry to hear what you went through and all along, you were only trying to improve your quality of life. Glad to hear that you are getting relief from pain. Best to you as well, take care. Ed

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@marvininhouston

The way that I understand it is that if you have PN from a compressed disc, once you remove the compression, the nerve can regenerate. I think the amount of time that the nerve was under stress plays a role also. In my case, the doctor said that my muscles did not atrophy and he hopes that once the nerve regenerates itself, reconnects, I should gain strength back in my right foot (of which I currentlyfail the 'big toe test'). He said I might have to deal with the pain, numbness, pins and needles forever, however, I'm seeing other YouTube doctors say it can recover. Therefore, I'm trying to maximize my chances by the right diet, nerve gliding/flossing, PT, exercise and vitamins that promote the healing.
Except for this self inflicted PN because I waited too long to have L4/L5 surgery, I am very healthy. Knock on wood ...
I do not think the nerves regenerate themselves when you get PN from diabetes, RA medicine, chemo or the like.
This is what I understand from reading. It's not like doctors are overwhelming anybody with information. There's a doctor above that was noted as 'great'. If they were that great, why are you here seeking answers? I had to read on and off for a few months, came up with a series of questions, and before I get done asking, it seemed like my time was up. Not sure when patients have PN why can't doctors just give you a standard diet to follow, vitamins to take, and immediately refer you to PT. Such as alpha lipoic acid shows get for diabetic PN but not compression PN. I guess if they gave out standard information I wouldn't be making return visits ... ugh

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The Peripheral Neuropathy Foundation just received money from Congress to help with research. No one has really done much research on the topic in a long time. I don't know if an answer will be found in time to help me but I keep looking. It has been almost two years since my spinal surgery and so far I have not felt any relief from the pain and burning in my feet. But the good thing is that the neuropathy has not progressed as I have heard that it can.

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@26sabrina

The Peripheral Neuropathy Foundation just received money from Congress to help with research. No one has really done much research on the topic in a long time. I don't know if an answer will be found in time to help me but I keep looking. It has been almost two years since my spinal surgery and so far I have not felt any relief from the pain and burning in my feet. But the good thing is that the neuropathy has not progressed as I have heard that it can.

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Did you have the neuropathy from your back?

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That was the final conclusion. That the degeneration of the L4L5 was most likely the cause of my “idiopathic “ peripheral neuropathy

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I’ve posted this before.
If anyone has had prolonged exposure to harsh chemicals have your blood checked for toxins. I did and had my blood cleaned about 80 percent through chelation. My numbness was up to both knees but after treatment it’s only the bottom of my feet. No pain. It’s been 18 years and not progressed. Gabapentin allows me to play tennis competitively at age 81. I hope this helps a few if you.

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I have stenosis at L4-5 on both sides and neuropathy in both feet, ankles and calves. Several doctors have looked at my stenosis and told me it's not bad enough to warrant surgery, or to cause my neuropathy. I wouldn't want surgery anyway since fusion or the insertion of a rod in your backbone would, for me anyway, only lead to more neuropathy. I say this because when I broke my left ankle and right talus bone (in foot), my neuropathy got much worse. Insertion of a plate and screw in the left ankle really made a mess of things - now I have internal scar tissue that gums up my nerves, muscles and blood vessels. This cannot be fixed by further surgery. I already have pain in my lower back - I don't need insertion of a rod to make it worse. Frankly, I don't think back surgeons have a clue. I've heard of far more failed back surgeries than successes. I suspect my neuropathy is the result of multiple factors including the bone breaks, two genetic mutations, mitochondrial dysfunction, multiple toxic medications that I take for other chronic diseases, and neuroinflammation caused by the medications. My plan at this point is to strengthen back muscles with core exercises, doing anti-inflammatory diet, doing self lymphathic massage to help reduce toxic meds, lose more weight, and take a variety of supplements including a mitochondrial cocktail to support my mito function. I also do a lot of research online in google scholar to try to identify any new approaches that might help - right now I'm looking into exosomes which are supposed to improve nerve axon and sheath regrowth and reduce neuroinflammation. In my case, there does not seem to be a single silver bullet, and surgery for me seems like a bad idea. Maybe for others, it may be a magical fix. Hope you find a simple solution.

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@margaret10

I have stenosis at L4-5 on both sides and neuropathy in both feet, ankles and calves. Several doctors have looked at my stenosis and told me it's not bad enough to warrant surgery, or to cause my neuropathy. I wouldn't want surgery anyway since fusion or the insertion of a rod in your backbone would, for me anyway, only lead to more neuropathy. I say this because when I broke my left ankle and right talus bone (in foot), my neuropathy got much worse. Insertion of a plate and screw in the left ankle really made a mess of things - now I have internal scar tissue that gums up my nerves, muscles and blood vessels. This cannot be fixed by further surgery. I already have pain in my lower back - I don't need insertion of a rod to make it worse. Frankly, I don't think back surgeons have a clue. I've heard of far more failed back surgeries than successes. I suspect my neuropathy is the result of multiple factors including the bone breaks, two genetic mutations, mitochondrial dysfunction, multiple toxic medications that I take for other chronic diseases, and neuroinflammation caused by the medications. My plan at this point is to strengthen back muscles with core exercises, doing anti-inflammatory diet, doing self lymphathic massage to help reduce toxic meds, lose more weight, and take a variety of supplements including a mitochondrial cocktail to support my mito function. I also do a lot of research online in google scholar to try to identify any new approaches that might help - right now I'm looking into exosomes which are supposed to improve nerve axon and sheath regrowth and reduce neuroinflammation. In my case, there does not seem to be a single silver bullet, and surgery for me seems like a bad idea. Maybe for others, it may be a magical fix. Hope you find a simple solution.

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Based on my experience that’s a good course to take. Surgery on hands and feet is some of the most painful you can have. Many bones and nerves to navigate. I have had both and it was way worse than my hips being replaced
Core strength and nutrition will play a big role in keeping PN as under control as possible

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@melissa59

Did you have the neuropathy from your back?

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It is unclear but a theory. If you read through, you will see many stories. It is why it is idiopathic. It is one of the things the Foundation is working on, what causes it.

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