← Return to Ovarian carcinoma: Continue with Zejula (Niraparib) or not?

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Ovarian carcinoma: Continue with Zejula (Niraparib) or not?

Gynecologic Cancers | Last Active: Dec 12, 2023 | Replies (25)
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@bendeb

<p>I was on Zejula for 3 yrs after chemo for stage 2/3 ovarian cancer. My Dr said I should stop because it can cause blood cancer. Has anyone stayed on past 3 years?</p>

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Colleen Young, Connect Director | @colleenyoung | Nov 18, 2023

@bendeb, according to Zejula's website:
"ZEJULA may cause serious side effects, including "bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of blood cancer called Acute Myeloid Leukemia (AML). Some people who have ovarian cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during treatment with ZEJULA." https://zejula.com/side-effects/#:~:text=Bone%20marrow%20problems%20called%20Myelodysplastic,AML%20during%20treatment%20with%20ZEJULA.

I believe members like @dorota52 @riteofscot @jbickler @sallyr have experience with Zejula (niraparib) as maintenance therapy and may have been on it for longer than 3 years.

Has your doctor noticed changes that put you at higher risk for developing a blood cancer? What treatment alternative is being suggested for you?

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