Hi Everyone - I have ovarian cancer that had mets to abdominal wall including omentum, diaphragm, bowel and various other areas of abdominal wall. Too extensive for surgery. After 4 rounds of chemo (carboplatin and Abraxane, which is albumin-bound paclitaxol) my cancer has practically disappeared. CT scans show absent, resolved, greatly diminished, etc. Docs tell me this is an excellent response. Scheduled for debunking surgery for complete hysterectomy and possible resection of diaphragm, and unlikely but possible resection of lower bowel. CA125 went from almost 3,000 to 17. I'm very optimistic - surgery is 11/30 and I feel very encouraged. BRCA1 negative, I do have a few mutations, don't know yet about HRD. Dene I understand so well about the fear, and having to live with the ambiguity of this disease. It's life changing... but not necessarily a death sentence! Women are surviving this, I'm working with a yoga instructor who is 10 years post stage 3 ovarian, and she's the picture of health and has been disease free all this time. She's a beacon, and please try to remind your wife not to look to the internet for answers... that can be scary and depressing! How are you both holding up?