Have you tried switching back to taking your entire prednisone dose in the morning?

After I managed to get below 10 mg, I wasn't having that much morning PMR pain anymore. Granted, I was taking the biologic to be able to stay on that low of a prednisone dose. The biologic didn't interfere with my adrenal function like prednisone did.

At 7 mg of prednisone, I was more concerned about adrenal insufficiency based on the information I was getting from someone who had an adrenal crisis. I think taking the entire dose of prednisone in the context of adrenal insufficiency is important.

Your adrenals need to be nudged into producing cortisol again. This happens in the middle of the night when you sleep. Your cortisol level should be lowest in the middle of the night. The normal function of the circadian rhythm is for your cortisol level to gradually increase until you wake up.

If pain wakes you up then that is something else.

It just depends on how much PMR inflammation you have on 7 mg of prednisone. Hopefully your adrenals will sense a lower cortisol level in the middle of the night and produce some cortisol. If your PMR pain is controlled during the night, maybe taking your entire prednisone dose in the morning when you wake up would be better from an adrenal standpoint.