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What's your experience with Orgovyx (relugolix)?
Prostate Cancer | Last Active: 4 hours ago | Replies (185)Comment receiving replies
No, sorry about the shorthand. My initial treatment (and only treatment thus far) was five fractions of radiation treatment of the entire prostate gland called stereotactic body radiotherapy (SBRT). That was combined with androgen deprivation therapy (ADT) using the drug Orgovyx, which my radiation oncologist started on the first day of radiation treatment. I'll be on that for a total of six months which for me will end early January 2024. My side effects have been manageable. I attribute that mostly to a healthy diet and daily physical activity. Best wishes and please feel free to reach out if you have any additional questions!
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Orgovyx: I have some good news and thought that I would share it.
Salvage Radiation tx together with 4 mos ADT Orgovyx Feb - June 2023.
Following RP Aug 2022 w/ immediate 90 day postop BCR of .19.
Nov 2023: uPSA test undetectable at < .02 and Testosterone 274 (up from undetectable in Mar < 2.5 w/ Orgovyx)
Feb 2024: uPSA test continues undetectable at < .02 and Testosterone 347 (80% of pretreatment tx level).
Extremely pleased; and hoping for continued remission of my G 9 PCa w/ Extraprostatic Extension.
Orgovyx experience was "as advertised": Rapid reduction of PSA and Testosterone upon starting.
Dissipation of ADT SEs 95% (mild to moderate for me; still sucked) 4 - 8 mos after stopping.
We go from PSA test to PSA test, and my PCa is anticipated to raise its ugly head again at some point, but hoping/praying for extended remission and next generation treatments.
Best to all.