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What's your experience with Orgovyx (relugolix)?

Prostate Cancer | Last Active: May 16 10:19am | Replies (135)

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@maverick75

I've been on Orgovyx for almost 4 months now on a 6 month treatment plan. I'm localized, 4+3, .69 decipher, 70. Treatment at Mayo Jax. I started Orgovyx on my first day of SBRT. I asked for a T-check blood work at the 15-day point just to be sure it was working as advertised-- it was. Was having problems sleeping with the hot flashes and some depression. Doc added Venflaxine which has helped significantly. Just had my first PSA check Friday post SBRT. PSA was undetectable! All going well. If the science showed a longer dose of ADT had significant benefit, I'd go longer. However, my RO believes we are being aggressive with the 6 months of ADT so I plan to stop in January.

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Replies to "I've been on Orgovyx for almost 4 months now on a 6 month treatment plan. I'm..."

Maverick75:
An I understanding your msg: You are having Salvage radiation treatment for BCR together with 6 mos Orgovyx?
Apologies; the acronyms are not always clear to me.
I have my 1st PSA test this morning following salvage tx after prostatectomy. My treatment was 38 sessions of IMRT radiation to the whole pelvic floor and pelvic lymph nodes together with 4 mos Orgovyx, so I am very interested.
Congratulations on the undetectable PSA result.