I am on third AI exemestane which I am tolerating. The hand joint pain in the night wakes me up . It does go away after 30 minutes in the morning. The anastrozole and Letrozole were painful head to toe ! The past year I had lumpectomy (2nd one) chemo and radiation . ER + So I will need the pill for 5 years . I feel like I got over every hurdle fine till I went on pill …5 years is a long time . I just had yearly mammogram and NO suspicious masses !!! I will continue herceptin till March then have port removed . This is a great place to read what others are going through to know you’re not alone. The lingo is so foreign when you’re scared and trying to find your through it all . Thanks to all who put the info on their journey here .