On Anastrozole I have mild and manageable joint stiffness (mostly in hips) that I could mitigate with walking and yoga stretching. I also have mild night sweats sometimes and mild insomnia sometimes. After one year these symptoms increased dramatically… after two months I decided to check everything I was taking in such as food and supplements etc. it turned out my pharmacy changed the manufacturer for anastrazole and my newly dramatic side effects coincided with this change. I found a pharmacy that could order the original manufacturer, and began looking into the brand name. Now that I’m back on the original my side effects receded back to mild/manageable.

So… when there is a change in your response to a med check any changes in generic manufacturing. Generic us not regulated in the same way as brand meds and they can fluctuate in main ingredient as much as 20% ( I’m told by a company rep) in either direction. Also they have different fillers. It would be nice if this were more tightly regulated.

Brand is always better but OMG $1700.00/mo vs $25.00/mo at CVS!