I have the same question, after hearing Dr. Scholz and Dr. Moyer discuss this on a PCRI video. They said "a study" showed the equivalent efficacy of taking one-half the dosage of Abiraterone with a healthy breakfast. They chuckled that everyone is excited about the results--except the drug companies. So far I have not been able to find the study. (Parenthetically, it would be nice if it also meant one-half the dose of Prednisone.) I will message my P.A. at Mayo to see what they recommend.