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@meags

I had hormonal resistant cancer and am now on letrozol 2.5 mg daily. My hands and wrists are suffering especially at night.
I am unable to make a fist as my fingers get to a point before the stretching/ locking pain is too much.
I have debilitating constant sharp pain through the tendon in my wrist aswell. Help please

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Replies to "I had hormonal resistant cancer and am now on letrozol 2.5 mg daily. My hands and..."

Hello @meags ,
I'm on 1mg of anastrozole for the past 20 months (among other things). I've had trigger fingers on my right hand and was referred to an orthopedist. I did 2 months of occupational therapy first (wrapped my hand in heated blankets, hand massage, massage with an ultrasonic vibration tool), wore a splint. It felt good during the therapy but only worked briefly so she injected cortisone to my finger and I've been -mostly- fine. When I make a fist with my hands, I can feel the difference between the left and the right. My right hand is a bit numb and stiff. Mine is bad especially in the mornings.

Try an orthopedist who works on hands. Mine was aware of the aromatase inhibitor side effects.

My husband has a different type of cancer but also suffers from neuropathy, so I thought I would see if I could think of anything that was recommended for him. I believe that his doctors told him that taking vitamin B6 may slow down the damage. Have you been told that or tried that? I will ask him if he recalls them recommending anything else.

Good morning
No I actually haven’t. But worth looking into. I have had to stop taking my Letrozole to see if the pain stops. Fingers crossed it does and it’s not permanent.
Unfortunately I do have to continue with some form of hormone tablet.
One day at a time I guess

Hi @meags, there are several helpful discussions about neuropathy both in the Breast Cancer support group and the Cancer: Managing Symptoms support group.

You might find these helpful:
https://connect.mayoclinic.org/search/discussions/?search=Neuropathy+and+chemo